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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
24.55
Human Site:
Y359
Identified Species:
36
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
Y359
F
T
E
M
D
P
T
Y
S
P
A
A
L
P
Q
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
Y451
F
T
E
M
D
P
T
Y
S
P
A
A
L
P
Q
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
Y617
F
T
E
M
D
P
T
Y
S
P
A
A
L
P
Q
Dog
Lupus familis
XP_547953
806
90703
Y366
F
T
E
M
D
P
T
Y
S
P
A
A
L
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
Y342
F
T
R
L
E
P
V
Y
S
P
A
G
S
P
P
Rat
Rattus norvegicus
Q63531
735
82865
Y321
E
I
K
R
H
I
F
Y
S
T
I
D
W
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
N304
P
S
I
L
F
K
R
N
A
A
I
I
D
P
L
Chicken
Gallus gallus
Q5F3L1
789
89022
Y349
F
T
E
M
D
P
T
Y
S
P
A
A
T
P
Q
Frog
Xenopus laevis
P10665
733
82620
F321
E
I
K
R
Q
P
F
F
S
T
I
D
W
N
K
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
K333
F
S
T
I
D
W
N
K
L
Y
R
R
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D571
F
T
D
Q
V
P
E
D
P
E
C
D
A
P
P
Honey Bee
Apis mellifera
XP_395099
910
102507
D381
F
T
K
M
I
A
A
D
S
P
A
V
V
P
P
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
Y325
F
T
S
Q
P
P
L
Y
S
P
A
E
S
P
L
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
D317
F
T
S
L
V
P
A
D
S
P
A
D
I
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
H83
G
P
S
L
V
V
S
H
S
L
K
M
N
K
L
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
I289
K
I
N
T
N
Q
D
I
H
L
D
S
F
H
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
53.3
13.3
N.A.
6.6
93.3
13.3
20
N.A.
26.6
46.6
53.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
66.6
26.6
N.A.
26.6
93.3
33.3
33.3
N.A.
33.3
60
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
13
0
7
7
57
32
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
7
0
38
0
7
19
0
0
7
25
7
0
0
% D
% Glu:
13
0
32
0
7
0
7
0
0
7
0
7
7
0
0
% E
% Phe:
69
0
0
0
7
0
13
7
0
0
0
0
7
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
7
0
0
7
7
0
0
0
0
7
0
% H
% Ile:
0
19
7
7
7
7
0
7
0
0
19
7
7
0
0
% I
% Lys:
7
0
19
0
0
7
0
7
0
0
7
0
0
7
19
% K
% Leu:
0
0
0
25
0
0
7
0
7
13
0
0
25
7
25
% L
% Met:
0
0
0
38
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
0
7
0
7
7
0
0
0
0
7
13
0
% N
% Pro:
7
7
0
0
7
63
0
0
7
57
0
0
0
69
19
% P
% Gln:
0
0
0
13
7
7
0
0
0
0
0
0
0
0
38
% Q
% Arg:
0
0
7
13
0
0
7
0
0
0
7
7
0
0
0
% R
% Ser:
0
13
19
0
0
0
7
0
75
0
0
7
13
0
0
% S
% Thr:
0
63
7
7
0
0
32
0
0
13
0
0
7
0
0
% T
% Val:
0
0
0
0
19
7
7
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _